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The repressor MDBP-2 is a member of the histone H1 family that binds preferentially in vitro and in vivo to methylated nonspecific DNA sequences.

MDBP-2 is a repressor that binds preferentially to methylated DNA. Peptides derived from MDBP-2 were sequenced. The sequences of the two peptides, KPAGPS-VTELITK and ALAAGGYDVEK, are identical to those found in the chicken histone H1 core protein. In SDS/polyacrylamide gels MDBP-2 has an apparent mo...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Jost, J P, Hofsteenge, J
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1992
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50159/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409659/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.20.9499
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