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Locally excitable Cdc42 signals steer cells during chemotaxis
Neutrophils and other amoeboid cells chemotax by steering their front towards chemoattractant. While Ras, Rac, Cdc42, and RhoA small GTPases all regulate chemotaxis, it has been unclear how they spatiotemporally control polarization and steering. Using fluorescence biosensors in neutrophil-like PLB-...
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| Veröffentlicht in: | Nat Cell Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5015690/ https://ncbi.nlm.nih.gov/pubmed/26689677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3292 |
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