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Mass Spectrometric Analysis of Surface-Exposed Regions in the Hexadecameric Phosphorylase Kinase Complex

Phosphorylase kinase (PhK) is a 1.3 MDa (αβγδ)(4) enzyme complex, in which αβγδ protomers associate in D2 symmetry to form two large octameric lobes that are interconnected by four bridges. The approximate locations of the subunits have been mapped in low-resolution cryo-electron microscopy structur...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Rimmer, Mary Ashley, Artigues, Antonio, Nadeau, Owen W., Villar, Maria T., Vasquez-Montes, Victor, Carlson, Gerald M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015440/
https://ncbi.nlm.nih.gov/pubmed/26551836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00682
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