Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies

BACKGROUND: Artemisinin resistance in Plasmodium falciparum lengthens parasite clearance half-life during artemisinin monotherapy or artemisinin-based combination therapy. Absence of in-vitro and ex-vivo correlates of artemisinin resistance hinders study of this phenotype. We aimed to assess whether...

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Udgivet i:Lancet Infect Dis
Main Authors: Witkowski, Benoit, Amaratunga, Chanaki, Khim, Nimol, Sreng, Sokunthea, Chim, Pheaktra, Kim, Saorin, Lim, Pharath, Mao, Sivanna, Sopha, Chantha, Sam, Baramey, Anderson, Jennifer M, Duong, Socheat, Chuor, Char Meng, Taylor, Walter R J, Suon, Seila, Mercereau-Puijalon, Odile, Fairhurst, Rick M, Menard, Didier
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015432/
https://ncbi.nlm.nih.gov/pubmed/24035558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(13)70252-4
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