Zofenopril Protects Against Myocardial Ischemia–Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability

BACKGROUND: Zofenopril, a sulfhydrylated angiotensin‐converting enzyme inhibitor (ACEI), reduces mortality and morbidity in infarcted patients to a greater extent than do other ACEIs. Zofenopril is a unique ACEI that has been shown to increase hydrogen sulfide (H(2)S) bioavailability and nitric oxid...

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Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Donnarumma, Erminia, Ali, Murtuza J., Rushing, Amanda M., Scarborough, Amy L., Bradley, Jessica M., Organ, Chelsea L., Islam, Kazi N., Polhemus, David J., Evangelista, Stefano, Cirino, Giuseppe, Jenkins, J. Stephen, Patel, Rajan A. G., Lefer, David J., Goodchild, Traci T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015391/
https://ncbi.nlm.nih.gov/pubmed/27381758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003531
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