Zofenopril Protects Against Myocardial Ischemia–Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability

BACKGROUND: Zofenopril, a sulfhydrylated angiotensin‐converting enzyme inhibitor (ACEI), reduces mortality and morbidity in infarcted patients to a greater extent than do other ACEIs. Zofenopril is a unique ACEI that has been shown to increase hydrogen sulfide (H(2)S) bioavailability and nitric oxid...

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Bibliografske podrobnosti
izdano v:J Am Heart Assoc
Main Authors: Donnarumma, Erminia, Ali, Murtuza J., Rushing, Amanda M., Scarborough, Amy L., Bradley, Jessica M., Organ, Chelsea L., Islam, Kazi N., Polhemus, David J., Evangelista, Stefano, Cirino, Giuseppe, Jenkins, J. Stephen, Patel, Rajan A. G., Lefer, David J., Goodchild, Traci T.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015391/
https://ncbi.nlm.nih.gov/pubmed/27381758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003531
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