Nitrite Therapy Ameliorates Myocardial Dysfunction via H(2)S and Nuclear Factor‐Erythroid 2‐Related Factor 2 (Nrf2)‐Dependent Signaling in Chronic Heart Failure

BACKGROUND: Bioavailability of nitric oxide (NO) and hydrogen sulfide (H(2)S) is reduced in heart failure (HF). Recent studies suggest cross‐talk between NO and H(2)S signaling. We previously reported that sodium nitrite (NaNO (2)) ameliorates myocardial ischemia‐reperfusion injury and HF. Nuclear f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Heart Assoc
Prif Awduron: Donnarumma, Erminia, Bhushan, Shashi, Bradley, Jessica M., Otsuka, Hiroyuki, Donnelly, Erinn L., Lefer, David J., Islam, Kazi N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015282/
https://ncbi.nlm.nih.gov/pubmed/27473036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003551
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