Nitrite Therapy Ameliorates Myocardial Dysfunction via H(2)S and Nuclear Factor‐Erythroid 2‐Related Factor 2 (Nrf2)‐Dependent Signaling in Chronic Heart Failure

BACKGROUND: Bioavailability of nitric oxide (NO) and hydrogen sulfide (H(2)S) is reduced in heart failure (HF). Recent studies suggest cross‐talk between NO and H(2)S signaling. We previously reported that sodium nitrite (NaNO (2)) ameliorates myocardial ischemia‐reperfusion injury and HF. Nuclear f...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Am Heart Assoc
Main Authors: Donnarumma, Erminia, Bhushan, Shashi, Bradley, Jessica M., Otsuka, Hiroyuki, Donnelly, Erinn L., Lefer, David J., Islam, Kazi N.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015282/
https://ncbi.nlm.nih.gov/pubmed/27473036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003551
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