Nitrite Therapy Ameliorates Myocardial Dysfunction via H(2)S and Nuclear Factor‐Erythroid 2‐Related Factor 2 (Nrf2)‐Dependent Signaling in Chronic Heart Failure

BACKGROUND: Bioavailability of nitric oxide (NO) and hydrogen sulfide (H(2)S) is reduced in heart failure (HF). Recent studies suggest cross‐talk between NO and H(2)S signaling. We previously reported that sodium nitrite (NaNO (2)) ameliorates myocardial ischemia‐reperfusion injury and HF. Nuclear f...

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Dades bibliogràfiques
Publicat a:J Am Heart Assoc
Autors principals: Donnarumma, Erminia, Bhushan, Shashi, Bradley, Jessica M., Otsuka, Hiroyuki, Donnelly, Erinn L., Lefer, David J., Islam, Kazi N.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015282/
https://ncbi.nlm.nih.gov/pubmed/27473036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003551
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