Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure

BACKGROUND: Metabolic impairment is an important contributor to heart failure (HF) pathogenesis and progression. Dysregulated metabolic pathways remain poorly characterized in patients with HF and preserved ejection fraction (HFpEF). We sought to determine metabolic abnormalities in HFpEF and identi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Am Heart Assoc
Main Authors: Hunter, Wynn G., Kelly, Jacob P., McGarrah, Robert W., Khouri, Michel G., Craig, Damian, Haynes, Carol, Ilkayeva, Olga, Stevens, Robert D., Bain, James R., Muehlbauer, Michael J., Newgard, Christopher B., Felker, G. Michael, Hernandez, Adrian F., Velazquez, Eric J., Kraus, William E., Shah, Svati H.
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2016
נושאים:
Original Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015273/
https://ncbi.nlm.nih.gov/pubmed/27473038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.003190
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