Characterization of a pathway-specific activator of milbemycin biosynthesis and improved milbemycin production by its overexpression in Streptomyces bingchenggensis

BACKGROUND: Milbemycins, a group of 16-membered macrolides with potent anthelminthic and insecticidal activity, are produced by several Streptomyces and used widely in agricultural, medical and veterinary fields. Milbemycin A3 and A4, the main components produced by Streptomyces bingchenggensis, hav...

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Detaylı Bibliyografya
Yayımlandı:Microb Cell Fact
Asıl Yazarlar: Zhang, Yanyan, He, Hairong, Liu, Hui, Wang, Haiyan, Wang, Xiangjing, Xiang, Wensheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015266/
https://ncbi.nlm.nih.gov/pubmed/27604457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0552-1
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