Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits

We propose a method (fastBAT) that performs a fast set-based association analysis for human complex traits using summary-level data from genome-wide association studies (GWAS) and linkage disequilibrium (LD) data from a reference sample with individual-level genotypes. We demonstrate using simulatio...

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Publicado en:Sci Rep
Autores principales: Bakshi, Andrew, Zhu, Zhihong, Vinkhuyzen, Anna A. E., Hill, W. David, McRae, Allan F., Visscher, Peter M., Yang, Jian
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015118/
https://ncbi.nlm.nih.gov/pubmed/27604177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32894
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