Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding

The surface envelope glycoprotein (SU) of Human immunodeficiency virus type 1 (HIV-1), gp120(SU) plays an essential role in virus binding to target CD4+ T-cells and is a major vaccine target. Gp120 has remarkably high levels of N-linked glycosylation and there is considerable evidence that this “gly...

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Publicado no:Sci Rep
Main Authors: Panico, Maria, Bouché, Laura, Binet, Daniel, O’Connor, Michael-John, Rahman, Dinah, Pang, Poh-Choo, Canis, Kevin, North, Simon J., Desrosiers, Ronald C., Chertova, Elena, Keele, Brandon F., Bess, Julian W., Lifson, Jeffrey D., Haslam, Stuart M., Dell, Anne, Morris, Howard R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015092/
https://ncbi.nlm.nih.gov/pubmed/27604319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32956
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