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Glucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine
Cancer cells have altered metabolism compared to normal cells, including dependence on glutamine (GLN) for survival, known as GLN addiction. However, some cancer cell lines do not require GLN for survival and the basis for this discrepancy is not well understood. GLN is a precursor for antioxidants...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5015067/ https://ncbi.nlm.nih.gov/pubmed/27605385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32606 |
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