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Therapeutically targeting mitochondrial redox signalling alleviates endothelial dysfunction in preeclampsia

Aberrant placentation generating placental oxidative stress is proposed to play a critical role in the pathophysiology of preeclampsia. Unfortunately, therapeutic trials of antioxidants have been uniformly disappointing. There is provisional evidence implicating mitochondrial dysfunction as a source...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: McCarthy, Cathal, Kenny, Louise C.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015016/
https://ncbi.nlm.nih.gov/pubmed/27604418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32683
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