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Therapeutically targeting mitochondrial redox signalling alleviates endothelial dysfunction in preeclampsia

Aberrant placentation generating placental oxidative stress is proposed to play a critical role in the pathophysiology of preeclampsia. Unfortunately, therapeutic trials of antioxidants have been uniformly disappointing. There is provisional evidence implicating mitochondrial dysfunction as a source...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: McCarthy, Cathal, Kenny, Louise C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015016/
https://ncbi.nlm.nih.gov/pubmed/27604418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32683
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