Population Pharmacokinetics and Exposure–Response (Efficacy and Safety/Tolerability) of Empagliflozin in Patients with Type 2 Diabetes

INTRODUCTION: The aim of the analysis was to characterize the population pharmacokinetics (PKs) and exposure–response (E–R) for efficacy (fasting plasma glucose, glycated hemoglobin) and safety/tolerability [hypoglycemia, genital infections, urinary tract infection (UTI), and volume depletion] of th...

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Detalhes bibliográficos
Publicado no:Diabetes Ther
Main Authors: Baron, Kyle T., Macha, Sreeraj, Broedl, Uli C., Nock, Valerie, Retlich, Silke, Riggs, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Healthcare 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014782/
https://ncbi.nlm.nih.gov/pubmed/27312794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13300-016-0174-y
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