Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: the relation to Alzheimer’s disease pathology

INTRODUCTION: We investigated change in DNA methylation in peripheral blood CD4+ lymphocytes over time, examined the relation between CD4+ lymphocytes and brain methylation, and compared their associations with AD pathology. METHODS: Genome-wide methylation was measured three times in 41 older perso...

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Publicat a:Alzheimers Dement
Autors principals: Yu, Lei, Chibnik, Lori, Yang, Jingyun, McCabe, Cristin, Xu, Jishu, Schneider, Julie A, De Jager, Philip L, Bennett, David A
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014706/
https://ncbi.nlm.nih.gov/pubmed/27016692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2016.02.009
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