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Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage.

Despite increasing evidence for a pathogenetic role for the beta-amyloid precursor protein (beta APP) in Alzheimer disease, the physiological function of the protein remains unclear. The expression of the neural-specific isoform containing 695 amino acids, beta APP695, is consistent with a role for...

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Detaylı Bibliyografya
Asıl Yazarlar: Hung, A Y, Koo, E H, Haass, C, Selkoe, D J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1992
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC50147/
https://ncbi.nlm.nih.gov/pubmed/1409654
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