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Pharmacogenetics of Efavirenz Discontinuation for Reported Central Nervous System Symptoms Appears to Differ by Race

BACKGROUND: Efavirenz frequently causes central nervous system (CNS) symptoms. We evaluated genetic associations with efavirenz discontinuation for CNS symptoms within 12 months of treatment initiation. METHODS: Patients had initiated efavirenz-containing regimens at an HIV primary care clinic in th...

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Bibliografiske detaljer
Udgivet i:Pharmacogenet Genomics
Main Authors: Leger, Paul, Chirwa, Sanika, Turner, Megan, Richardson, Danielle M., Baker, Paxton, Leonard, Michael, Erdem, Husamettin, Olson, Lana, Haas, David W.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014672/
https://ncbi.nlm.nih.gov/pubmed/27509478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000238
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