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Fractionation spares mice from radiation-induced reductions in weight gain but does not prevent late oligodendrocyte lineage side effects

PURPOSE: To determine the late effects of fractionated versus single dose cranial radiation on murine white matter. METHODS AND MATERIALS: Mice were exposed to 0 Gy, 6×6 Gy, or 1×20 Gy cranial irradiation at 10–12 weeks of age. Endpoints were assessed through 18 months from exposure using immunohist...

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Publicat a:Int J Radiat Oncol Biol Phys
Autors principals: Begolly, Sage, Shrager, Peter G., Olschowka, John A., Williams, Jacqueline P., O’Banion, M. Kerry
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014650/
https://ncbi.nlm.nih.gov/pubmed/27478169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2016.05.005
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