Brain radiation injury leads to a dose- and time-dependent recruitment of peripheral myeloid cells that depends on CCR2 signaling

BACKGROUND: Cranial radiotherapy is used to treat tumors of the central nervous system (CNS), as well as non-neoplastic conditions such as arterio-venous malformations; however, its use is limited by the tolerance of adjacent normal CNS tissue, which can lead to devastating long-term sequelae for pa...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Moravan, Michael J., Olschowka, John A., Williams, Jacqueline P., O’Banion, M. Kerry
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738790/
https://ncbi.nlm.nih.gov/pubmed/26842770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0496-8
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