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An Efficient Method for Generation of Transgenic Rats Avoiding Embryo Manipulation

Although rats are preferred over mice as an animal model, transgenic animals are generated predominantly using mouse embryos. There are limitations in the generation of transgenic rat by embryo manipulation. Unlike mouse embryos, most of the rat embryos do not survive after male pronuclear DNA injec...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Pradhan, Bhola Shankar, Majumdar, Subeer S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014465/
https://ncbi.nlm.nih.gov/pubmed/27111419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.9
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