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An Efficient Method for Generation of Transgenic Rats Avoiding Embryo Manipulation

Although rats are preferred over mice as an animal model, transgenic animals are generated predominantly using mouse embryos. There are limitations in the generation of transgenic rat by embryo manipulation. Unlike mouse embryos, most of the rat embryos do not survive after male pronuclear DNA injec...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Pradhan, Bhola Shankar, Majumdar, Subeer S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014465/
https://ncbi.nlm.nih.gov/pubmed/27111419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.9
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