Topical Use of Angiopoietin-like Protein 2 RNAi-loaded Lipid Nanoparticles Suppresses Corneal Neovascularization

Corneal neovascularization (CNV) is a sight-threatening condition that is encountered in various inflammatory settings including chemical injury. We recently confirmed that angiopoietin-like protein 2 (ANGPTL2) is a potent angiogenic and proinflammatory factor in the cornea, and we have produced a s...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Taketani, Yukako, Usui, Tomohiko, Toyono, Tetsuya, Shima, Nobuyuki, Yokoo, Seiichi, Kimakura, Mikiko, Yamagami, Satoru, Ohno, Shinichiro, Onodera, Risako, Tahara, Kohei, Takeuchi, Hirofumi, Kuroda, Masahiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014459/
https://ncbi.nlm.nih.gov/pubmed/27111418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.1
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