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Modelling modal gating of ion channels with hierarchical Markov models

Many ion channels spontaneously switch between different levels of activity. Although this behaviour known as modal gating has been observed for a long time it is currently not well understood. Despite the fact that appropriately representing activity changes is essential for accurately capturing ti...

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Detalhes bibliográficos
Publicado no:Proc Math Phys Eng Sci
Main Authors: Siekmann, Ivo, Fackrell, Mark, Crampin, Edmund J., Taylor, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society Publishing 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014102/
https://ncbi.nlm.nih.gov/pubmed/27616917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspa.2016.0122
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