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Translational neurophysiology in sheep: measuring sleep and neurological dysfunction in CLN5 Batten disease affected sheep

Creating valid mouse models of slowly progressing human neurological diseases is challenging, not least because the short lifespan of rodents confounds realistic modelling of disease time course. With their large brains and long lives, sheep offer significant advantages for translational studies of...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Perentos, Nicholas, Martins, Amadeu Q., Watson, Thomas C., Bartsch, Ullrich, Mitchell, Nadia L., Palmer, David N., Jones, Matthew W., Morton, A. Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014075/
https://ncbi.nlm.nih.gov/pubmed/25724202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv026
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