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Linear models of activation cascades: analytical solutions and coarse-graining of delayed signal transduction
Cellular signal transduction usually involves activation cascades, the sequential activation of a series of proteins following the reception of an input signal. Here, we study the classic model of weakly activated cascades and obtain analytical solutions for a variety of inputs. We show that in the...
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| Veröffentlicht in: | J R Soc Interface |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Royal Society
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5014067/ https://ncbi.nlm.nih.gov/pubmed/27581482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2016.0409 |
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