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Stochastic models of gene transcription with upstream drives: exact solution and sample path characterization

Gene transcription is a highly stochastic and dynamic process. As a result, the mRNA copy number of a given gene is heterogeneous both between cells and across time. We present a framework to model gene transcription in populations of cells with time-varying (stochastic or deterministic) transcripti...

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Detalhes bibliográficos
Publicado no:J R Soc Interface
Main Authors: Dattani, Justine, Barahona, Mauricio
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310734/
https://ncbi.nlm.nih.gov/pubmed/28053113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2016.0833
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