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Stochastic models of gene transcription with upstream drives: exact solution and sample path characterization

Gene transcription is a highly stochastic and dynamic process. As a result, the mRNA copy number of a given gene is heterogeneous both between cells and across time. We present a framework to model gene transcription in populations of cells with time-varying (stochastic or deterministic) transcripti...

詳細記述

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書誌詳細
出版年:J R Soc Interface
主要な著者: Dattani, Justine, Barahona, Mauricio
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310734/
https://ncbi.nlm.nih.gov/pubmed/28053113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2016.0833
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