RPTOR, a novel target of miR-155, elicits a fibrotic phenotype of cystic fibrosis lung epithelium by upregulating CTGF

Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the most frequent of which is F508del-CFTR. CF is characterized by excessive secretion of pro-inflammatory mediators into the airway lumen, inducing a h...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Tsuchiya, Motohiro, Kalurupalle, Swathi, Kumar, Parameet, Ghoshal, Sarani, Zhang, Yongqing, Lehrmann, Elin, Becker, Kevin G., Gorospe, Myriam, Biswas, Roopa
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013987/
https://ncbi.nlm.nih.gov/pubmed/27284727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1197484
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