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Deciphering the associations between gene expression and copy number alteration using a sparse double Laplacian shrinkage approach

Motivation: Both gene expression levels (GEs) and copy number alterations (CNAs) have important biological implications. GEs are partly regulated by CNAs, and much effort has been devoted to understanding their relations. The regulation analysis is challenging with one gene expression possibly regul...

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Pubblicato in:Bioinformatics
Autori principali: Shi, Xingjie, Zhao, Qing, Huang, Jian, Xie, Yang, Ma, Shuangge
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013934/
https://ncbi.nlm.nih.gov/pubmed/26342102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv518
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