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Diminishing-returns epistasis among random beneficial mutations in a multicellular fungus

Adaptive evolution ultimately is fuelled by mutations generating novel genetic variation. Non-additivity of fitness effects of mutations (called epistasis) may affect the dynamics and repeatability of adaptation. However, understanding the importance and implications of epistasis is hampered by the...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Biol Sci
Hauptverfasser: Schoustra, Sijmen, Hwang, Sungmin, Krug, Joachim, de Visser, J. Arjan G. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013798/
https://ncbi.nlm.nih.gov/pubmed/27559062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2016.1376
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