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Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining
MHC tetramers are an essential tool for characterizing antigen-specific CD4+ T cells. However, their ex vivo analysis is limited by the large sample requirements. Here we demonstrate a combinatorial staining approach that allows simultaneous characterization of multiple specificities to address this...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013714/ https://ncbi.nlm.nih.gov/pubmed/27571776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12614 |
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