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Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization

It is currently not possible to predict which epitopes will be recognized by T cells in different individuals. This is a barrier to the thorough analysis and understanding of T-cell responses after vaccination or infection. Here, by combining mass cytometry with combinatorial peptide–MHC tetramer st...

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Detalhes bibliográficos
Main Authors: Newell, Evan W, Sigal, Natalia, Nair, Nitya, Kidd, Brian A, Greenberg, Harry B, Davis, Mark M
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796952/
https://ncbi.nlm.nih.gov/pubmed/23748502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2593
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