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Insulin post-transcriptionally modulates Bmal1 protein to affect the hepatic circadian clock
Although food availability is a potent synchronizer of the peripheral circadian clock in mammals, the underlying mechanisms are unclear. Here, we show that hepatic Bmal1, a core transcription activator of the molecular clock, is post-transcriptionally regulated by signals from insulin, an important...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013695/ https://ncbi.nlm.nih.gov/pubmed/27576939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12696 |
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