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Gentamicin-Induced Ototoxicity and Nephrotoxicity Vary with Circadian Time of Treatment and Entail Separate Mechanisms

The aminoglycoside antibiotic gentamicin can cause both ototoxicity and nephrotoxicity, the severity of which varies with circadian time of daily treatment. However, it is not yet resolved if such drug-induced adverse effects are independent or dependent phenomena. Two groups of 9 female Sprague-Daw...

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Detalhes bibliográficos
Publicado no:Chronobiol Int
Main Authors: Blunston, Mary A., Yonovitz, Al, Woodahl, Erica L., Smolensky, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013539/
https://ncbi.nlm.nih.gov/pubmed/26506922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/07420528.2015.1082483
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