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G-actin guides p53 nuclear transport: potential contribution of monomeric actin in altered localization of mutant p53

p53 preserves genomic integrity by restricting anomaly at the gene level. Till date, limited information is available for cytosol to nuclear shuttling of p53; except microtubule-based trafficking route, which utilizes minus-end directed motor dynein. The present study suggests that monomeric actin (...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Saha, Taniya, Guha, Deblina, Manna, Argha, Panda, Abir Kumar, Bhat, Jyotsna, Chatterjee, Subhrangsu, Sa, Gaurisankar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013524/
https://ncbi.nlm.nih.gov/pubmed/27601274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32626
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