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TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis
There is now compelling evidence that TNFR2 is constitutively expressed on CD4(+) Foxp3(+) regulatory T cells (Tregs) and TNF-TNFR2 interaction is critical for the activation, expansion and functional stability of Tregs. However, we showed that the expression of TNFR2 was also up-regulated on CD4(+)...
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Gepubliceerd in: | Sci Rep |
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Hoofdauteurs: | , , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Nature Publishing Group
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013387/ https://ncbi.nlm.nih.gov/pubmed/27601345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32834 |
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