Melatonin prevents acute kidney injury in severely burned rats via the activation of SIRT1

Acute kidney injury (AKI) is a common complication after severe burns. Melatonin has been reported to protect against multiple organ injuries by increasing the expression of SIRT1, a silent information regulator that regulates stress responses, inflammation, cellular senescence and apoptosis. This s...

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Pubblicato in:Sci Rep
Autori principali: Bai, Xiao-Zhi, He, Ting, Gao, Jian-Xin, Liu, Yang, Liu, Jia-Qi, Han, Shi-Chao, Li, Yan, Shi, Ji-Hong, Han, Jun-Tao, Tao, Ke, Xie, Song-Tao, Wang, Hong-Tao, Hu, Da-Hai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013284/
https://ncbi.nlm.nih.gov/pubmed/27599451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32199
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