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Melatonin prevents acute kidney injury in severely burned rats via the activation of SIRT1
Acute kidney injury (AKI) is a common complication after severe burns. Melatonin has been reported to protect against multiple organ injuries by increasing the expression of SIRT1, a silent information regulator that regulates stress responses, inflammation, cellular senescence and apoptosis. This s...
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| Опубликовано в: : | Sci Rep |
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| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013284/ https://ncbi.nlm.nih.gov/pubmed/27599451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32199 |
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