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Midazolam-Ketamine Dual Therapy Stops Cholinergic Status Epilepticus And Reduces Morris Water Maze Deficits
OBJECTIVE: Pharmacoresistance remains an unsolved therapeutic challenge in status epilepticus (SE) and in cholinergic SE induced by nerve agent intoxication. SE triggers a rapid internalization of synaptic GABA(A) receptors and externalization of NMDA receptors that may explain the loss of potency o...
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| Publié dans: | Epilepsia |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5012923/ https://ncbi.nlm.nih.gov/pubmed/27500978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13480 |
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