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Treatment of experimental status epilepticus with synergistic drug combinations

During status epilepticus (SE), synaptic GABA(A) receptors (GABA(A)R) become internalized and inactive, while spare NMDA receptors (NMDAR) assemble, move to the membrane and become synaptically active. When treatment of SE is delayed, the number of synaptic GABA(A)R is drastically reduced, and a GAB...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Niquet, Jerome, Baldwin, Roger, Suchomelova, Lucie, Lumley, Lucille, Eavey, Roland, Wasterlain, Claude G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386805/
https://ncbi.nlm.nih.gov/pubmed/28225161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13695
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