Shikonin Induces Apoptotic Cell Death via Regulation of p53 and Nrf2 in AGS Human Stomach Carcinoma Cells

Shikonin, which derives from Lithospermum erythrorhizon, has been traditionally used against a variety of diseases, including cancer, in Eastern Asia. Here we determined that shikonin inhibits proliferation of gastric cancer cells by inducing apoptosis. Shikonin’s biological activity was validated b...

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Bibliografiske detaljer
Udgivet i:Biomol Ther (Seoul)
Main Authors: Ko, Hyeonseok, Kim, Sun-Joong, Shim, So Hee, Chang, HyoIhl, Ha, Chang Hoon
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Society of Applied Pharmacology 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012875/
https://ncbi.nlm.nih.gov/pubmed/27257011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2016.008
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