DNA Mismatch Repair Deficiency in Rectal Cancer: Benchmarking Its Impact on Prognosis, Neoadjuvant Response Prediction, and Clinical Cancer Genetics

PURPOSE: DNA mismatch repair deficiency (dMMR) hallmarks consensus molecular subtype 1 of colorectal cancer. It is being routinely tested, but little is known about dMMR rectal cancers. The efficacy of novel treatment strategies cannot be established without benchmarking the outcomes of dMMR rectal...

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Pubblicato in:J Clin Oncol
Autori principali: de Rosa, Nicole, Rodriguez-Bigas, Miguel A., Chang, George J., Veerapong, Jula, Borras, Ester, Krishnan, Sunil, Bednarski, Brian, Messick, Craig A., Skibber, John M., Feig, Barry W., Lynch, Patrick M., Vilar, Eduardo, You, Y. Nancy
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2016
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ORIGINAL REPORTS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012714/
https://ncbi.nlm.nih.gov/pubmed/27432916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.66.6826
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