The Envelope Cytoplasmic Tail of HIV-1 Subtype C Contributes to Poor Replication Capacity through Low Viral Infectivity and Cell-to-Cell Transmission

The cytoplasmic tail (gp41CT) of the HIV-1 envelope (Env) mediates Env incorporation into virions and regulates Env intracellular trafficking. Little is known about the functional impact of variability in this domain. To address this issue, we compared the replication of recombinant virus pairs carr...

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Publicat a:PLoS One
Autors principals: Santos da Silva, Eveline, Mulinge, Martin, Lemaire, Morgane, Masquelier, Cécile, Beraud, Cyprien, Rybicki, Arkadiusz, Servais, Jean-Yves, Iserentant, Gilles, Schmit, Jean-Claude, Seguin-Devaux, Carole, Perez Bercoff, Danielle
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012655/
https://ncbi.nlm.nih.gov/pubmed/27598717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161596
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