The Envelope Cytoplasmic Tail of HIV-1 Subtype C Contributes to Poor Replication Capacity through Low Viral Infectivity and Cell-to-Cell Transmission

The cytoplasmic tail (gp41CT) of the HIV-1 envelope (Env) mediates Env incorporation into virions and regulates Env intracellular trafficking. Little is known about the functional impact of variability in this domain. To address this issue, we compared the replication of recombinant virus pairs carr...

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Bibliographic Details
Published in:PLoS One
Main Authors: Santos da Silva, Eveline, Mulinge, Martin, Lemaire, Morgane, Masquelier, Cécile, Beraud, Cyprien, Rybicki, Arkadiusz, Servais, Jean-Yves, Iserentant, Gilles, Schmit, Jean-Claude, Seguin-Devaux, Carole, Perez Bercoff, Danielle
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012655/
https://ncbi.nlm.nih.gov/pubmed/27598717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161596
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