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Prediction of accrual closure date in multi-center clinical trials with discrete-time Poisson process models

In a phase III multi-center cancer clinical trial or large public health studies, sample size is predetermined to achieve desired power and study participants are enrolled from tens or hundreds of participating institutions. As the accrual is closing to the target size, the coordinating data center...

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Bibliografske podrobnosti
izdano v:Pharm Stat
Main Authors: Tang, Gong, Kong, Yuan, Chang, Chung-Chou Ho, Kong, Lan, Costantino, Joseph P.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012647/
https://ncbi.nlm.nih.gov/pubmed/22411544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1506
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