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Prediction of accrual closure date in multi-center clinical trials with discrete-time Poisson process models

In a phase III multi-center cancer clinical trial or large public health studies, sample size is predetermined to achieve desired power and study participants are enrolled from tens or hundreds of participating institutions. As the accrual is closing to the target size, the coordinating data center...

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Bibliografische gegevens
Gepubliceerd in:Pharm Stat
Hoofdauteurs: Tang, Gong, Kong, Yuan, Chang, Chung-Chou Ho, Kong, Lan, Costantino, Joseph P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012647/
https://ncbi.nlm.nih.gov/pubmed/22411544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1506
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