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In vivo assessment of bone marrow toxicity by gold nanoparticle-based bioconjugates in Crl:CD1(ICR) mice

INTRODUCTION: The present study aimed at evaluating the biodistribution of Tween(®) 20-gold nanoparticle (GNP) conjugates and their potential toxicity on the bone marrow before moving on to Phase I clinical trials. MATERIALS AND METHODS: Tween(®) 20-conjugated GNPs were injected intravenously for 21...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Berce, Cristian, Lucan, Ciprian, Petrushev, Bobe, Boca, Sanda, Miclean, Mirela, Sarpataki, Orsolya, Astilean, Simion, Buzoianu, Anca, Tomuleasa, Ciprian, Bojan, Anca
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012637/
https://ncbi.nlm.nih.gov/pubmed/27621620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S108711
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