MDM2–MDM4 molecular interaction investigated by atomic force spectroscopy and surface plasmon resonance

Murine double minute 2 (MDM2) and 4 (MDM4) are known as the main negative regulators of p53, a tumor suppressor. They are able to form heterodimers that are much more effective in the downregulation of p53. Therefore, the MDM2–MDM4 complex could be a target for promising therapeutic restoration of p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Nanomedicine
Päätekijät: Moscetti, Ilaria, Teveroni, Emanuela, Moretti, Fabiola, Bizzarri, Anna Rita, Cannistraro, Salvatore
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2016
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012629/
https://ncbi.nlm.nih.gov/pubmed/27621617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S114705
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia