Chloroquine improves left ventricle diastolic function in streptozotocin-induced diabetic mice

Diabetes is a potent risk factor for heart failure with preserved ejection fraction (HFpEF). Autophagy can be activated under pathological conditions, including diabetic cardiomyopathy. The therapeutic effects of chloroquine (CQ), an autophagy inhibitor, on left ventricle function in streptozotocin...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Yuan, Xun, Xiao, Yi-Chuan, Zhang, Gui-Ping, Hou, Ning, Wu, Xiao-Qian, Chen, Wen-Liang, Luo, Jian-Dong, Zhang, Gen-Shui
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012595/
https://ncbi.nlm.nih.gov/pubmed/27621594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S111253
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