Chloroquine improves left ventricle diastolic function in streptozotocin-induced diabetic mice

Diabetes is a potent risk factor for heart failure with preserved ejection fraction (HFpEF). Autophagy can be activated under pathological conditions, including diabetic cardiomyopathy. The therapeutic effects of chloroquine (CQ), an autophagy inhibitor, on left ventricle function in streptozotocin...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Yuan, Xun, Xiao, Yi-Chuan, Zhang, Gui-Ping, Hou, Ning, Wu, Xiao-Qian, Chen, Wen-Liang, Luo, Jian-Dong, Zhang, Gen-Shui
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012595/
https://ncbi.nlm.nih.gov/pubmed/27621594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S111253
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